Unfortunately, all cardiac surgeries may result in adverse outcomes, including death. The only large, published study describes a successful result in 38/40 patients (CSU), with no patient deaths (Potter et al. ACVIM abstract 2023). Patient deaths may be reported in the future in larger studies. Avoidance of an open-heart approach and avoidance of cardiopulmonary bypass makes the V-Clamp procedure lower risk than other methods of mitral valve repair.